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Brca1tm1Mak
Targeted Allele Detail
Nomenclature
Symbol: Brca1tm1Mak
Name: breast cancer 1, early onset; targeted mutation 1, Tak Mak
MGI ID: MGI:1858108
Synonyms: Brca15-6
Gene: Brca1  Location: Chr11:101488764-101551955 bp, - strand  Genetic Position: Chr11, 65.18 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:33880
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exons 5 and 6, encoding the zinc finger domain, with a neomycin cassette. (J:33880)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brca1 Mutation:  77 strains or lines available
References
Original:  J:33880 Hakem R, et al., The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse. Cell. 1996 Jun 28;85(7):1009-23
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory