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Mlh1tm1Lisk
Targeted Allele Detail
Nomenclature
Symbol: Mlh1tm1Lisk
Name: mutL homolog 1; targeted mutation 1, Michael Liskay
MGI ID: MGI:1857946
Synonyms: Mlh1-
Gene: Mlh1  Location: Chr9:111228228-111271791 bp, - strand  Genetic Position: Chr9, 60.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:34291
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Replacement of exon 4 with a Pgk-HPRT mini-gene. (J:34291)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mlh1 Mutation:  20 strains or lines available
References
Original:  J:34291 Baker SM, et al., Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over [see comments]. Nat Genet. 1996 Jul;13(3):336-42
All:  41 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory