Mgat3^tm1Jxm
Targeted Allele Detail

Summary

• Symbol: Mgat3^tm1Jxm
• Name: mannoside acetylglucosaminyltransferase 3; targeted mutation 1, Jamey Marth
• MGI ID: MGI:1857830
• Synonyms: Mgat3^delta
• Gene: Mgat3 Location: Chr15:80057922-80099720 bp, + strand Genetic Position: Chr15, 37.85 cM, cytoband E
• Alliance: Mgat3^tm1Jxm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:39067
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A construct was created in which loxP sites flanked the protein-encoding exon of the gene. After Cre recombinase treatment, the protein-encoding exon of the gene was excised, resulting in a null allele. (J:39067)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mgat3 Mutation: 32 strains or lines available

References

• Original: J:39067 Priatel JJ, et al., Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction. Glycobiology. 1997 Feb;7(1):45-56
• All: 9 reference(s)