About   Help   FAQ
Adcy1tm1Drs
Targeted Allele Detail
Nomenclature
Symbol: Adcy1tm1Drs
Name: adenylate cyclase 1; targeted mutation 1, Daniel R Storm
MGI ID: MGI:1857775
Synonyms: AC1-, I-AC-
Gene: Adcy1  Location: Chr11:7063489-7178506 bp, + strand  Genetic Position: Chr11, 4.72 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:22287
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection casssette replaced a genomic fragment including part of exon 1. Northern blot analysis demonstrated that the transcript was not detectable in RNA from homozygous mice. (J:22287)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy1 Mutation:  31 strains or lines available
References
Original:  J:22287 Wu ZL, et al., Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):220-4
All:  43 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory