About   Help   FAQ
En1tm2Alj
Targeted Allele Detail
Nomenclature
Symbol: En1tm2Alj
Name: engrailed 1; targeted mutation 2, Alexandra L Joyner
MGI ID: MGI:1857749
Synonyms: En1lki, En-1Lki, EnlacZ
Gene: En1  Location: Chr1:120530216-120535720 bp, + strand  Genetic Position: Chr1, 52.74 cM, cytoband C2-qter
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:27767
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsLacZ sequences were inserted downstream of the En1 promoter. The sequences corresponding to the first 111 amino acids of the reading frame are also deleted. (J:27767)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 150 assay results
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any En1 Mutation:  26 strains or lines available
References
Original:  J:27767 Hanks M, et al., Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science. 1995 Aug 4;269(5224):679-82
All:  24 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory