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Etn2Sd
Spontaneous Allele Detail
Summary
Symbol: Etn2Sd
Name: early transposon element insertion site 2; short Danforth
MGI ID: MGI:1857746
Synonyms: Sd(short-Danforth)
Gene: Etn2  Location: unknown  Genetic Position: Chr2, Syntenic
Alliance: Etn2Sd page
Etn2Sd/+

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  Danforth's posterior duplication stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Transposon insertion
 
Mutation detailsA retrotransposon highly homologous to murine early transposon (ETn) endogenous retrovirus (ERV) 3 (ETnERV3) inserted 12 kb upstream of Ptf1a resulting in over-expression. The transposon insertion also results in the over-expression of Gm13344 and Gm13336. (J:195133, J:195196, J:195197)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 299 assay results
In Structures Affected by this Mutation: 22 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Etn2 Mutation:  3 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Caudal regression syndrome (J:195133)
References
Original:  J:13055 Dunn LC, et al., A new mutation in the mouse affecting spinal column and urogenital system. J Hered. 1940;31:343-348
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory