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Targeted Allele Detail
Symbol: Colqtm1Jrs
Name: collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:1857733
Gene: Colq  Location: Chr14:31523082-31591343 bp, - strand  Genetic Position: Chr14, 19.18 cM, cytoband B
Synapses in some Colqtm1Jrs/Colqtm1Jrs muscle appear immature or fragmented

Show the 2 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:54006
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance cassette replaced 0.8 kb of sequence containing the exon encoding the proline rich domain. (J:54006)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Colq Mutation:  2 strains or lines available
Original:  J:54006 Feng G, et al., Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol. 1999 Mar 22;144(6):1349-60
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory