Colqtm1Jrs
Targeted Allele Detail
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Symbol: |
Colqtm1Jrs |
Name: |
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase; targeted mutation 1, Joshua R Sanes |
MGI ID: |
MGI:1857733 |
Gene: |
Colq Location: Chr14:31523082-31591343 bp, - strand Genetic Position: Chr14, 19.18 cM, cytoband B
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Synapses in some Colqtm1Jrs/Colqtm1Jrs muscle appear immature or fragmented
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:54006
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Parent Cell Line: |
R1 (ES Cell)
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Strain of Origin: |
(129X1/SvJ x 129S1/Sv)F1-Kitl+ |
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neomycin resistance cassette replaced 0.8 kb of sequence containing the exon encoding the proline rich domain.
(J:54006)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Colq Mutation: |
16 strains or lines available
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Original: |
J:54006 Feng G, et al., Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol. 1999 Mar 22;144(6):1349-60 |
All: |
5 reference(s) |
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