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Lig4tm1Icrf
Targeted Allele Detail
Nomenclature
Symbol: Lig4tm1Icrf
Name: ligase IV, DNA, ATP-dependent; targeted mutation 1, Imperial Cancer Research Fund
MGI ID: MGI:1857720
Synonyms: lig4-
Gene: Lig4  Location: Chr8:9970020-9976323 bp, - strand  Genetic Position: Chr8, 4.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:51608
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 8 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lig4 Mutation:  10 strains or lines available
Notes

ES cell line = GK129 (129P2/OlaHsd) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+).

References
Original:  J:51608 Barnes DE, et al., Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr Biol. 1998 Dec 17-31;8(25):1395-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory