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Wnt7atm1Amc
Targeted Allele Detail
Nomenclature
Symbol: Wnt7atm1Amc
Name: wingless-type MMTV integration site family, member 7A; targeted mutation 1, Andrew P McMahon
MGI ID: MGI:1857704
Synonyms: Wnt-7a
Gene: Wnt7a  Location: Chr6:91363981-91411363 bp, - strand  Genetic Position: Chr6, 40.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:23922
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin cassette was inserted into exon 2. Authors state that this is likely a null allele, but present no molecular evidence. (J:23922)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 75 assay results
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt7a Mutation:  10 strains or lines available
References
Original:  J:23922 Parr BA, et al., Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature. 1995 Mar 23;374(6520):350-3
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/17/2019
MGI 6.14
The Jackson Laboratory