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Smad3tm1Xfw
Targeted Allele Detail
Nomenclature
Symbol: Smad3tm1Xfw
Name: SMAD family member 3; targeted mutation 1, Xiao Fan Wang
MGI ID: MGI:1857696
Synonyms: Smad3-, Smad3null
Gene: Smad3  Location: Chr9:63646767-63757994 bp, - strand  Genetic Position: Chr9, 34.22 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:53948
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad3 Mutation:  3 strains or lines available
References
Original:  J:53948 Datto MB, et al., Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol Cell Biol. 1999 Apr;19(4):2495-504
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory