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Myogtm1Whk
Targeted Allele Detail
Nomenclature
Symbol: Myogtm1Whk
Name: myogenin; targeted mutation 1, William H Klein
MGI ID: MGI:1857667
Synonyms: Mygml, Myog-
Gene: Myog  Location: Chr1:134289989-134292548 bp, + strand  Genetic Position: Chr1, 58.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:14208
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin cassette was inserted into the first exon of the Myog locus, at a site corresponding to 25 codons downstream of the initiator methionine codon. The mutation was shown to eliminate expression of the gene. (J:14208)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 103 assay results
In Structures Affected by this Mutation: 14 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myog Mutation:  8 strains or lines available
References
Original:  J:14208 Hasty P, et al., Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene [see comments]. Nature. 1993 Aug 5;364(6437):501-6
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory