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Hoxa1tm1Ipc
Targeted Allele Detail
Nomenclature
Symbol: Hoxa1tm1Ipc
Name: homeobox A1; targeted mutation 1, Pierre Chambon
MGI ID: MGI:1857504
Synonyms: Hox-1.6-, Hoxa1null, Hoxa-1tot
Gene: Hoxa1  Location: Chr6:52155590-52158317 bp, - strand  Genetic Position: Chr6, 25.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:23837
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of nucleotides -49 to +373 relative to the transcription initiation site with a neomycin cassette. (J:23837)
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 234 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa1 Mutation:  7 strains or lines available
References
Original:  J:23837 Lufkin T, et al., Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell. 1991 Sep 20;66(6):1105-19
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory