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Gsctm1Pgr
Targeted Allele Detail
Summary
Symbol: Gsctm1Pgr
Name: goosecoid homeobox; targeted mutation 1, Peter Gruss
MGI ID: MGI:1857496
Gene: Gsc  Location: Chr12:104437468-104439495 bp, - strand  Genetic Position: Chr12, 54.32 cM
Alliance: Gsctm1Pgr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29421
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin cassette was inserted into exon 2, disrupting sequences encoding the homeodomain. (J:29421)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 17 assay results
In Structures Affected by this Mutation: 30 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Gsc Mutation:  15 strains or lines available
References
Original:  J:29421 Yamada G, et al., Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death. Development. 1995 Sep;121(9):2917-22
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory