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Kcne1tm1Sfh
Targeted Allele Detail
Nomenclature
Symbol: Kcne1tm1Sfh
Name: potassium voltage-gated channel, Isk-related subfamily, member 1; targeted mutation 1, Stephen F Heinemann
MGI ID: MGI:1857442
Synonyms: isk-, KCNE1-
Gene: Kcne1  Location: Chr16:92346001-92359468 bp, - strand  Genetic Position: Chr16, 53.57 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:37461
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced the entire coding region of the gene. (J:37461)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Kcne1 Mutation:  7 strains or lines available
References
Original:  J:37461 Vetter DE, et al., Inner ear defects induced by null mutation of the isk gene. Neuron. 1996 Dec;17(6):1251-64
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory