About   Help   FAQ
Htr2ctm1Jul
Targeted Allele Detail
Nomenclature
Symbol: Htr2ctm1Jul
Name: 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1, David Julius
MGI ID: MGI:1857439
Synonyms: 5-HT2cR-deficient
Gene: Htr2c  Location: ChrX:146962513-147197277 bp, + strand  Genetic Position: ChrX, 68.46 cM, cytoband D-F4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:24339
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Htr2c Mutation:  6 strains or lines available
Notes
ES cell line = D3 (129S2/SvPas) or J1 (129S4/SvJae).

References
Original:  J:24339 Tecott LH, et al., Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors [see comments]. Nature. 1995 Apr 6;374(6522):542-6
All:  32 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory