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Crhtm1Maj
Targeted Allele Detail
Nomenclature
Symbol: Crhtm1Maj
Name: corticotropin releasing hormone; targeted mutation 1, Joseph Majzoub
MGI ID: MGI:1857392
Synonyms: CRH -, CRHKO, CRH KO, CRH-KO
Gene: Crh  Location: Chr3:19693401-19695396 bp, - strand  Genetic Position: Chr3, 5.75 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:23082
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 70 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Crh Mutation:  25 strains or lines available
References
Original:  J:23082 Muglia L, et al., Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature. 1995 Feb 2;373(6513):427-32
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory