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Ednrbs-27Pub
Radiation induced Allele Detail
Nomenclature
Symbol: Ednrbs-27Pub
Name: endothelin receptor type B; Pu239 citrate alpha ray induced 27Pub
MGI ID: MGI:1857332
Synonyms: Ednrbs-21R, s27Pub
Gene: Ednrb  Location: Chr14:103814625-103844402 bp, - strand  Genetic Position: Chr14, 53.05 cM
Mutation
origin
Strain of Origin:  (101/Rl x C3H/Rl)F1
Mutation
description
Allele Type:    Radiation induced
Mutation:    Single point mutation
 
Mutation detailsA C-to-T transition mutation at nucleotide 854 is predicted to result in a proline to leucine substitution at residue 285 (P285L in TMV region). Neither of the flanking markers D14Mit38 and D14Mit42 (2 cM apart) was deleted in this mutation. (J:16291, J:44601)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ednrb Mutation:  53 strains or lines available
Notes
The allele was induced by irradiation of spermatogonia by [alpha-239]-Pu: Plutonium citrate (alpha particles).
References
Original:  J:16291 Metallinos DL, et al., Fine structure mapping and deletion analysis of the murine piebald locus. Genetics. 1994 Jan;136(1):217-23
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory