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Ednrbs-1Chlc
Chemically induced Allele Detail
Nomenclature
Symbol: Ednrbs-1Chlc
Name: endothelin receptor type B; chlorambucil 1Chlc
MGI ID: MGI:1857326
Synonyms: Ednrbs-11R, s1ChLc, sOR-9Q
Gene: Ednrb  Location: Chr14:103814625-103844173 bp, - strand  Genetic Position: Chr14, 53.05 cM
Mutation
origin
Strain of Origin:  (101/Rl x C3H/Rl)F1
Mutation
description
Allele Type:    Chemically induced (other)
Mutation:    Undefined
 
Mutation detailsNo molecular defect was detected. These mice produce normal levels of transcript in adult brain, suggesting that the mutation affects important regulatory elements that mediate the expression of the gene during development. No genomic alterations identified within ~ 1.25 megabases surrounding the locus. (J:44601)
Inheritance:    Recessive
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ednrb Mutation:  57 strains or lines available
References
Original:  J:10322 Rinchik EM, et al., Genetic and molecular analysis of chlorambucil-induced germ-line mutations in the mouse. Proc Natl Acad Sci U S A. 1990 Feb;87(4):1416-20
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory