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Targeted Allele Detail
Symbol: Relatm1Bal
Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian); targeted mutation 1, David Baltimore
MGI ID: MGI:1857270
Synonyms: Nfkb1tmBal, p65-, rela-
Gene: Rela  Location: Chr19:5637483-5648130 bp, + strand  Genetic Position: Chr19, 4.34 cM, cytoband B1-3
Germline Transmission:  Earliest citation of germline transmission: J:28390
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was disrupted using neomycin resistance cassette. The vector replaced sequences encoding most of exons 6, 8 and the entire exon 7. Protein was not detectable by Western analysis in embryonic fibroblast extracts from homozygous mutant animals. (J:28390)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 12 assay results
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rela Mutation:  20 strains or lines available
Original:  J:28390 Beg AA, et al., Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B. Nature. 1995 Jul 13;376(6536):167-70
All:  51 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory