About   Help   FAQ
Krastm1Tyj
Targeted Allele Detail
Nomenclature
Symbol: Krastm1Tyj
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 1, Tyler Jacks
MGI ID: MGI:1857210
Synonyms: K-ras-, K-rasKO, K-rastm1
Gene: Kras  Location: Chr6:145216699-145250239 bp, - strand  Genetic Position: Chr6, 77.37 cM, cytoband G2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43433
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 was replaced by a neomycin cassette. (J:43433)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kras Mutation:  32 strains or lines available
References
Original:  J:43433 Johnson L, et al., K-ras is an essential gene in the mouse with partial functional overlap with N-ras. Genes Dev. 1997 Oct 1;11(19):2468-81
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/14/2017
MGI 6.08
The Jackson Laboratory