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Krastm1Tyj
Targeted Allele Detail
Nomenclature
Symbol: Krastm1Tyj
Name: Kirsten rat sarcoma viral oncogene homolog; targeted mutation 1, Tyler Jacks
MGI ID: MGI:1857210
Synonyms: K-ras-, K-rasKO, K-rastm1
Gene: Kras  Location: Chr6:145216699-145250239 bp, - strand  Genetic Position: Chr6, 77.37 cM, cytoband G2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:43433
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 1 was replaced by a neomycin cassette. (J:43433)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kras Mutation:  32 strains or lines available
References
Original:  J:43433 Johnson L, et al., K-ras is an essential gene in the mouse with partial functional overlap with N-ras. Genes Dev. 1997 Oct 1;11(19):2468-81
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory