About   Help   FAQ
Il10tm1Cgn
Targeted Allele Detail
Nomenclature
Symbol: Il10tm1Cgn
Name: interleukin 10; targeted mutation 1, University of Cologne
MGI ID: MGI:1857199
Synonyms: Il10-, IL-10-, IL-10KO, IL-10KO, IL-10 KO, Il10tmCgn
Gene: Il10  Location: Chr1:131019845-131024974 bp, + strand  Genetic Position: Chr1, 56.89 cM
Characterization of Il10tm1Cgn/Il10tm1Cgn mice

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:15222
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 11 strains available      Cell Lines: 0 lines available
Carrying any Il10 Mutation:  17 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Idiopathic Inflammatory Bowel Disease (J:15222).

References
Original:  J:15222 Kuhn R, et al., Interleukin-10-deficient mice develop chronic enterocolitis [see comments]. Cell. 1993 Oct 22;75(2):263-74
All:  601 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory