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Il7rtm1Imx
Targeted Allele Detail
Nomenclature
Symbol: Il7rtm1Imx
Name: interleukin 7 receptor; targeted mutation 1, Immunex
MGI ID: MGI:1857198
Synonyms: CD127-, IL-7R-, IL7R-, IL-7Ralpha-
Gene: Il7r  Location: Chr15:9506161-9529876 bp, - strand  Genetic Position: Chr15, 4.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:21135
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin resistance cassette was inserted into exon 3 of the gene. (J:21135)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Il7r Mutation:  6 strains or lines available
References
Original:  J:21135 Peschon JJ, et al., Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med. 1994 Nov 1;180(5):1955-60
All:  107 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory