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Fmr1tm1Cgr
Targeted Allele Detail
Nomenclature
Symbol: Fmr1tm1Cgr
Name: fragile X mental retardation syndrome 1; targeted mutation 1, Ben Oostra
MGI ID: MGI:1857169
Synonyms: Fmr1 KO, Fmr1tm4Cgr, FMRP KO, fmr-tm1Cgr, FraX
Gene: Fmr1  Location: ChrX:68678541-68717963 bp, + strand  Genetic Position: ChrX, 34.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:19220
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Fmr1 Mutation:  21 strains or lines available
Notes
Genbank: AF179463 and AF170530

References
Original:  J:19220 Bakker CE, et al., Fmr1 knockout mice: a model to study fragile x mental retardation. The Dutch-Belgium Fragile X Consortium. Cell. 1994 Jul 15;78(1):23-33
All:  186 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory