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Drd1tm1Jcd
Targeted Allele Detail
Nomenclature
Symbol: Drd1tm1Jcd
Name: dopamine receptor D1; targeted mutation 1, John Drago
MGI ID: MGI:1857158
Synonyms: D1-, D1A-, D1r-
Gene: Drd1  Location: Chr13:54051186-54055658 bp, - strand  Genetic Position: Chr13, 28.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:22076
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance cassette replaced 0.75kb of sequence encoding the fifth transmembrane domain and third intracytoplasmic loop. (J:22076)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Drd1 Mutation:  35 strains or lines available
References
Original:  J:22076 Drago J, et al., Altered striatal function in a mutant mouse lacking D1A dopamine receptors. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12564-8
All:  55 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory