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Dnmt1tm1Jae
Targeted Allele Detail
Nomenclature
Symbol: Dnmt1tm1Jae
Name: DNA methyltransferase (cytosine-5) 1; targeted mutation 1, Rudolf Jaenisch
MGI ID: MGI:1857157
Synonyms: Dmntn, Dnmt1N, DnmtN, MTase(-), Mtasen
Gene: Dnmt1  Location: Chr9:20907206-20959888 bp, - strand  Genetic Position: Chr9, 7.66 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:1157
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Hypomorph)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Inheritance:    Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 64 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dnmt1 Mutation:  44 strains or lines available
References
Original:  J:1157 Li E, et al., Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 1992 Jun 12;69(6):915-26
All:  29 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory