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Btktm1Wk
Targeted Allele Detail
Nomenclature
Symbol: Btktm1Wk
Name: Bruton agammaglobulinemia tyrosine kinase; targeted mutation 1, Wasif Kahn
MGI ID: MGI:1857138
Synonyms: Btk-, Btk-kin-/GL, BtkM
Gene: Btk  Location: ChrX:134542336-134583570 bp, - strand  Genetic Position: ChrX, 56.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:28968
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Btk Mutation:  11 strains or lines available
References
Original:  J:28968 Khan WN, et al., Defective B cell development and function in Btk-deficient mice. Immunity. 1995 Sep;3(3):283-99
All:  67 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory