About   Help   FAQ
Radiation induced Allele Detail
Symbol: Cntnap1shm
Name: contactin associated protein-like 1; shambling
MGI ID: MGI:1857037
Gene: Cntnap1  Location: Chr11:101065429-101081550 bp, + strand  Genetic Position: Chr11, 64.33 cM, cytoband D
Alliance: Cntnap1shm page
Strain of Origin:  random-bred
Allele Type:    Radiation induced
Mutation:    Insertion
Mutation detailsThe molecular lesion is a TT insertion in exon 22. This introduces a frameshift in the encoded protein, resulting in an altered sequence of 45 amino acids at the C terminus, and a stop codon at residue 1287, resulting in the deletion of 98 amino acids from the C terminus of the mutant protein. (J:165697)
Inheritance:    Recessive
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cntnap1 Mutation:  34 strains or lines available
Original:  J:5040 Green EL, Shambling, a neurological mutant of the mouse. J Hered. 1967 Mar-Apr;58(2):65-8
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory