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Cntnap1shm
Radiation induced Allele Detail
Summary
Symbol: Cntnap1shm
Name: contactin associated protein-like 1; shambling
MGI ID: MGI:1857037
Gene: Cntnap1  Location: Chr11:101065429-101081550 bp, + strand  Genetic Position: Chr11, 64.33 cM, cytoband D
Alliance: Cntnap1shm page
Mutation
origin
Strain of Origin:  random-bred
Mutation
description
Allele Type:    Radiation induced
Mutation:    Insertion
 
Mutation detailsThe molecular lesion is a TT insertion in exon 22. This introduces a frameshift in the encoded protein, resulting in an altered sequence of 45 amino acids at the C terminus, and a stop codon at residue 1287, resulting in the deletion of 98 amino acids from the C terminus of the mutant protein. (J:165697)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cntnap1 Mutation:  34 strains or lines available
References
Original:  J:5040 Green EL, Shambling, a neurological mutant of the mouse. J Hered. 1967 Mar-Apr;58(2):65-8
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory