Mesd^mesd
Radiation induced Allele Detail

Summary

• Symbol: Mesd^mesd
• Name: mesoderm development LRP chaperone; mesoderm development
• MGI ID: MGI:1856955
• Synonyms: implantation survival, IS, msd
• Gene: Mesd Location: Chr7:83533074-83549519 bp, + strand Genetic Position: Chr7, 48.35 cM
• Alliance: Mesd^mesd page

Mutation origin

• Strain of Origin: (C3H/Rl x 101/Rl)F1

Mutation description

• Allele Type: Radiation induced
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mesd Mutation: 15 strains or lines available

Notes

Embryos homozygous for radiation induced deletions in the region of the tyrosinase locus (Tyr) which encompass the mesd locus are completely devoid of mesoderm, and begin to degenerate at about 11 days of gestation. Embryonic and extraembryonic ectoderms are present. mesd is the most proximal locus affected by Tyr deletions (J:1540).

References

• Original: J:1540 Klebig ML, et al., Physical analysis of murine albino deletions that disrupt liver-specific gene regulation or mesoderm development. Mamm Genome. 1992;2(1):51-63
• All: 3 reference(s)