About   Help   FAQ
Cftrtm1Hgu
Targeted Allele Detail
Nomenclature
Symbol: Cftrtm1Hgu
Name: cystic fibrosis transmembrane conductance regulator; targeted mutation 1, MRC Human Genetics Unit
MGI ID: MGI:1856710
Synonyms: cf, cftrm1HGU, Cftrm1Hgu, CftrTgH(neoim)1Hgu, CftrTgH(neoim)Hgu, EDI
Gene: Cftr  Location: Chr6:18170687-18322768 bp, + strand  Genetic Position: Chr6, 8.1 cM, cytoband A3
Generation 27 and 28 Cftrtm1Hgu/Cftrtm1Hgu mice exhibit focal hypertrophy of goblet cells

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:14614
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cftr Mutation:  13 strains or lines available
References
Original:  J:14614 Dorin JR, et al., Cystic fibrosis in the mouse by targeted insertional mutagenesis [see comments]. Nature. 1992 Sep 17;359(6392):211-5
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory