About   Help   FAQ
Sharpincpdm
Spontaneous Allele Detail
Nomenclature
Symbol: Sharpincpdm
Name: SHANK-associated RH domain interacting protein; chronic proliferative dermatitis
MGI ID: MGI:1856699
Synonyms: cpd, cpdm
Gene: Sharpin  Location: Chr15:76347040-76351111 bp, - strand  Genetic Position: Chr15, 35.75 cM
Mutation
origin
Strain of Origin:  C57BL/Ka
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsA single base pair deletion in the 3' end of exon 1 creates a shift in the open reading frame predicted to cause a premature stop codon at position 624. (J:121810)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 31 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sharpin Mutation:  18 strains or lines available
References
Original:  J:14539 HogenEsch H, et al., A spontaneous mutation characterized by chronic proliferative dermatitis in C57BL mice. Am J Pathol. 1993 Sep;143(3):972-82
All:  37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/05/2018
MGI 6.12
The Jackson Laboratory