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Cdk5rap2an
Radiation induced Allele Detail
Nomenclature
Symbol: Cdk5rap2an
Name: CDK5 regulatory subunit associated protein 2; Hertwig's anemia
MGI ID: MGI:1856646
Gene: Cdk5rap2  Location: Chr4:70135092-70328672 bp, - strand  Genetic Position: Chr4, 35.92 cM, cytoband C2
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Radiation induced (Modified isoform(s))
Mutations:    Intragenic deletion, Inversion
 
Mutation detailsExon 4 is inverted which results in an in-frame 111 bp deletion with the loss of exon 4 from the mRNA. Northern analysis demonstrated that exon 4 was uniformly omitted from the mutant mRNA. (J:160533)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cdk5rap2 Mutation:  62 strains or lines available
References
Original:  J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80:220-246
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory