Pou3f4^Slf
Radiation induced Allele Detail

Summary

• Symbol: Pou3f4^Slf
• Name: POU domain, class 3, transcription factor 4; sex linked fidget
• MGI ID: MGI:1856631
• Synonyms: Slf
• Gene: Pou3f4 Location: ChrX:109857886-109860813 bp, + strand Genetic Position: ChrX, 48.2 cM
• Alliance: Pou3f4^Slf page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Inversion
• Mutation details: The mutation in the sex linked fidget mouse is an X chromosomal inversion with one breakpoint close to Pou3f4. This inversion selectively eliminates the expression of the Pou3f4 gene in the developing inner ear, but not the neural tube. The mutation was also shown to be allelic to Pou3f4^tm1Cren. (J:59387)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou3f4 Mutation: 3 strains or lines available

References

• Original: J:13743 Phillips RJS, et al., Sex-linked fidget (Slf). Mouse News Lett. 1978;58:44
• All: 3 reference(s)