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Hrrh-8J
Spontaneous Allele Detail
Nomenclature
Symbol: Hrrh-8J
Name: hairless; rhino 8 Jackson
MGI ID: MGI:1856506
Gene: Hr  Location: Chr14:70552212-70573548 bp, + strand  Genetic Position: Chr14, 36.32 cM
Mutation
origin
Strain of Origin:  B10.D2-H2d/nSnJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Nucleotide substitutions
 
Mutation detailsMolecular analysis revealed that a GA-to-TT substitution at positions 1910 and 1911 had occurred. This is predicted to result in a glutamine to histidine amino acid substitution at position 511 and a lysine to stop codon subsitution at position 512. (J:50909)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hr Mutation:  57 strains or lines available
References
Original:  J:30778 Sweet HO, et al., Remutations at The Jackson Laboratory (Update to Mouse Genome 1993; 91:862-5 - J16313). Mouse Genome. 1995;93(4):1030-4
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory