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Lepob
Spontaneous Allele Detail
Nomenclature
Symbol: Lepob
Name: leptin; obese
MGI ID: MGI:1856424
Synonyms: ob, ob/ob
Gene: Lep  Location: Chr6:29060220-29073877 bp, + strand  Genetic Position: Chr6, 12.3 cM
Lepob/Lepob

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs
Mutation
description
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Single point mutation
 
Mutation details
Inheritance:    Recessive
Generation of the 5292035 allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 52 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 6 strains available      Cell Lines: 0 lines available
Carrying any Lep Mutation:  8 strains or lines available
References
Original:  J:13066 INGALLS AM, et al., Obese, a new mutation in the house mouse. J Hered. 1950 Dec;41(12):317-8
All:  841 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory