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Slc45a2Uw-dbr
Spontaneous Allele Detail
Nomenclature
Symbol: Slc45a2Uw-dbr
Name: solute carrier family 45, member 2; underwhite dominant brown
MGI ID: MGI:1856227
Synonyms: dbr
Gene: Slc45a2  Location: Chr15:11000721-11029233 bp, + strand  Genetic Position: Chr15, 5.4 cM
Slc45a2Uw-dbr/+ and Slc45a2Uw-dbr/Slc45a2Uw-dbr

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  B10.PL-H2u/(73NS)Sn
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsMolecular analysis reveals a G to A transition in codon 153, resulting in the substitution of a highly conserved aspartic acid to asparagine. The substitution occurs near the cytoplasmic face of transmembrane domain 4, adjacent to the loop containing the sucrose transporter signature sequence. (J:72440)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:  41 strains or lines available
References
Original:  J:13967 MacPike A, et al., New coat color mutations, Dbr and cht. Mouse News Lett. 1984;70:86
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory