Pax1^un-ex
Spontaneous Allele Detail

Summary

• Symbol: Pax1^un-ex
• Name: paired box 1; undulated extensive
• MGI ID: MGI:1856223
• Synonyms: hump-back syndrome and wavy tail, un^ex
• Gene: Pax1 Location: Chr2:147203850-147216972 bp, + strand Genetic Position: Chr2, 72.63 cM
• Alliance: Pax1^un-ex page

Mutation origin

• Strain of Origin: Peru-Coppock stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This allele comprises a deletion of at least 28.2 kb including exon 5 and the polyadenylation signal. Analyses of mutant mice indicated truncated transcript expressed at levels lower than those of wild-type. Endogenous protein was undetected in homozygous mutant mice, however the potential for a mutant protein not detected by the antiserum remained. (J:23331)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax1 Mutation: 28 strains or lines available

References

• Original: J:15087 Wallace ME, un, undulated. Mouse News Lett. 1979;61:29
• All: 9 reference(s)