About   Help   FAQ
Pax6Sey-Neu
Chemically induced Allele Detail
Nomenclature
Symbol: Pax6Sey-Neu
Name: paired box 6; small eye, Neuherberg
MGI ID: MGI:1856158
Synonyms: ENU-2029, Pax6-, Pax61-NeuSey, Pax6Sey-1Neu, Pax6Sey-Neu1, Sey1N, Sey-neu, SeyNeu
Gene: Pax6  Location: Chr2:105668900-105697364 bp, + strand  Genetic Position: Chr2, 55.31 cM
Mutation
origin
Strain of Origin:  (102/El x C3H/Rl)F1
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation details
Inheritance:    Semidominant
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 24 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pax6 Mutation:  36 strains or lines available
Notes
Chimeric mice created from BALB/c and Pax6Sey/Sey-Neu exhibit reduction in lens and nasal epithelium tissue size, abnormal optic cup morphology and exclusion of Pax6Sey/Sey-Neu cells from the lens, nasal epithelium and retinal pigmented epithelium (J:31747).

References
Original:  J:177480 Favor J, et al., The effect of dose fractionation on the frequency of ethylnitrosourea-induced dominant cataract and recessive specific locus mutations in germ cells of the mouse. Mutat Res. 1988 Apr;198(2):269-75
All:  61 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory