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Vsx2or-2J
Spontaneous Allele Detail
Nomenclature
Symbol: Vsx2or-2J
Name: visual system homeobox 2; ocular retardation 2 Jackson
MGI ID: MGI:1856113
Gene: Vsx2  Location: Chr12:84616602-84642231 bp, + strand  Genetic Position: Chr12, 39.28 cM
Mutation
origin
Strain of Origin:  NOR/LtDn
Mutation
description
Allele Type:    Spontaneous
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vsx2 Mutation:  24 strains or lines available
Notes
A remutation at the Chx10 locus occurred in NOR/LtDn, a genetically contaminated subline of the nonobese diabetic NOD/Lt strain. Eye phenotypes in homozygotes resemble the eye abnormalities reported in Chx10or-J/Chx10or-J homozygotes. NOR-Chx10or-2J/Chx10or-2J homozygotes of both sexes are infertile and show defective germ cell maturation. Chx10or-J/Chx10or-2J heterozygotes are fully fertile in both sexes (J:30714).
References
Original:  J:30714 Prochazka M, et al., or-2J; a new remutation at ocular retardation (or) associated with sterility. Mouse Genome. 1990;87:93
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory