Atrn^mg
Spontaneous Allele Detail

Summary

• Symbol: Atrn^mg
• Name: attractin; mahogany
• MGI ID: MGI:1856081
• Synonyms: mg
• Gene: Atrn Location: Chr2:130748415-130872253 bp, + strand Genetic Position: Chr2, 63.26 cM
• Alliance: Atrn^mg page

Mutation origin

• Strain of Origin: C3H x Swiss stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: This allele comprises a 5 kb insertion in a 3' to 5'orientation in intron 26, downstream of the exons encoding the transmembrane domain. The insertion was identified as an intracisternal A particle (IAP) transposon. Northern hybridization results predict that the insertion affects normal splicing. Western analysis of whole brain extracts from homozygous mice show an Atrn protein that migrates slightly faster than normal Atrn. (J:71075)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Atrn Mutation: 89 strains or lines available

References

• Original: J:103 Lane PW, et al., Mahogany, a recessive color mutation in linkage group V of the mouse. J Hered. 1960;51(5):228-230
• All: 12 reference(s)