About   Help   FAQ
Sgk3fz
Spontaneous Allele Detail
Nomenclature
Symbol: Sgk3fz
Name: serum/glucocorticoid regulated kinase 3; fuzzy
MGI ID: MGI:1856038
Gene: Sgk3  Location: Chr1:9868332-9971070 bp, + strand  Genetic Position: Chr1, 2.08 cM
Mutation
origin
Strain of Origin:  CFW stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsThis mutation comprises insertion of a single adenine following nucleotide 579 of the cDNA sequence, in a region encoded by exon 10 of the gene, that causes a shift in the amino acid reading frame and premature termination of protein translation following leucine 192 (Leu192Ter), which resides in the serine/threonine kinase domain. (J:125551)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Sgk3 Mutation:  23 strains or lines available
References
Original:  J:90 DICKIE MM, et al., Fuzzy mice. J Hered. 1950 Jul;41(7):193-6
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/16/2021
MGI 6.17
The Jackson Laboratory