About   Help   FAQ
Due to maintenance, access to MGI may be intermittent 8:00 AM ET Wed, September 18.
ax
Radiation induced Allele Detail
Nomenclature
Symbol: ax
Name: nonagouti; lethal nonagouti
MGI ID: MGI:1855944
Synonyms: a(x)
Gene: a  Location: Chr2:154950204-155051012 bp, + strand  Genetic Position: Chr2, 76.83 cM
Mutation
origin
Strain of Origin:  (C3H/Rl x 101/Rl)F1
Mutation
description
Allele Type:    Radiation induced
Mutation:    Intergenic deletion
 
Mutation detailsThis allele comprises a deletion of approximately 100 kb, which does not affect agouti coding sequences, but begins 4 kb 3' of the last exon, and thus may affect coat color by removing an agouti 3' enhancer. The Ahcy gene, which codes for the enzyme S-adenosylhomocysteine hydrolase (SAHase), is contained within a 20 kb region within the a(x) deletion. (J:17867)
Inheritance:    Other (see notes)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any a Mutation:  416 strains or lines available
Notes
ax is recessive to Ay, Aw, A, and at, and dominant to a.
References
Original:  J:174047 Russell LB, et al., Crossing over within the a "locus" of the mouse. Genetics. 1963;48:907 Abstr
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/10/2019
MGI 6.14
The Jackson Laboratory