Summary | Mutation origin | Mutation description | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Csnk1a1tm1.2Ybn
Name:	casein kinase 1, alpha 1; targeted mutation 1.2, Yinon Ben-Neriah
MGI ID:	MGI:5543668
Gene:	Csnk1a1  Location: Chr18:61688345-61723132 bp, + strand  Genetic Position: Chr18, 34.62 cM, cytoband D3
Alliance:	Csnk1a1tm1.2Ybn page

Germline Transmission:	Earliest citation of germline transmission: J:204886
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin resistance cassette was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the neomycin resistance cassette and exon 2. (J:204886)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Csnk1a1tm1.2Ybn

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csnk1a1 Mutation:	38 strains or lines available

Original:	J:204886 Elyada E, et al., CKIalpha ablation highlights a critical role for p53 in invasiveness control. Nature. 2011 Feb 17;470(7334):409-13
All:	1 reference(s)