Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gtf2h5tm1.1Wive
Name:	general transcription factor IIH, polypeptide 5; targeted mutation 1.1, Wim Vermeulen
MGI ID:	MGI:5514340
Synonyms:	Ttda-
Gene:	Gtf2h5  Location: Chr17:6130103-6135763 bp, + strand  Genetic Position: Chr17, 3.7 cM
Alliance:	Gtf2h5tm1.1Wive page

Germline Transmission:	Earliest citation of germline transmission: J:200022
Parent Cell Line:	IB10/E14IB10 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin resistance cassette replaced the coding sequence in exon 3. Cre-mediated recombination removed the neomycin resistance cassette. (J:200022)

Generation of the Gtf2h5tm1.1Wive allele

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gtf2h5 Mutation:	13 strains or lines available

Original:	J:200022 Theil AF, et al., Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality. PLoS Genet. 2013 Apr;9(4):e1003431
All:	2 reference(s)