Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tab3tm1Aki
Name:	TGF-beta activated kinase 1/MAP3K7 binding protein 3; targeted mutation 1, Shizuo Akira
MGI ID:	MGI:5502690
Gene:	Tab3  Location: ChrX:84617628-84678075 bp, + strand  Genetic Position: ChrX, 39.32 cM, cytoband B
Alliance:	Tab3tm1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:195289
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Almost all of exons 2 and 3 were replaced by a neomycin resistance cassette. Absence of mRNA in properly targeted mice was confirmed by PCR. (J:195289)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tab3 Mutation:	13 strains or lines available

Original:	J:195289 Ori D, et al., Essential Roles of K63-Linked Polyubiquitin-Binding Proteins TAB2 and TAB3 in B Cell Activation via MAPKs. J Immunol. 2013 Apr 15;190(8):4037-45
All:	1 reference(s)