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Stard10tm1Saaa
Targeted Allele Detail
Summary
Symbol: Stard10tm1Saaa
Name: StAR related lipid transfer domain containing 10; targeted mutation 1, Satomi Adachi-Akahane
MGI ID: MGI:5500937
Gene: Stard10  Location: Chr7:100966293-100995833 bp, + strand  Genetic Position: Chr7, 54.55 cM
Alliance: Stard10tm1Saaa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198860
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette replaced exons 3 through 5. Western blot analysis confirmed the absence of protein expression in the liver. (J:198860)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stard10 Mutation:  21 strains or lines available
References
Original:  J:198860 Ito M, et al., Disruption of Stard10 gene alters the PPARalpha-mediated bile acid homeostasis. Biochim Biophys Acta. 2013 Feb;1831(2):459-68
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory