Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pstpip1tm1.1Dtg
Name:	proline-serine-threonine phosphatase-interacting protein 1; targeted mutation 1.1, Douglas T Golenbock
MGI ID:	MGI:5496137
Synonyms:	Pstpip1 del
Gene:	Pstpip1  Location: Chr9:55997246-56036172 bp, + strand  Genetic Position: Chr9, 30.13 cM, cytoband C
Alliance:	Pstpip1tm1.1Dtg page

Germline Transmission:	Earliest citation of germline transmission: J:196002
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre-mediated recombination removed exons 4 through 11. Western blot analysis confirmed the absence of protein expression in the thymus, spleen and bone marrow. (J:196002)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pstpip1 Mutation:	14 strains or lines available

Original:	J:196002 Wang D, et al., Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins. J Biol Chem. 2013 Feb 15;288(7):4594-601
All:	1 reference(s)