Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hormad2tm1Kura
Name:	HORMA domain containing 2; targeted mutation 1, Hiroki Kurahashi
MGI ID:	MGI:5466566
Gene:	Hormad2  Location: Chr11:4295814-4391105 bp, - strand  Genetic Position: Chr11, 2.94 cM, cytoband A1
Alliance:	Hormad2tm1Kura page

Germline Transmission:	Earliest citation of germline transmission: J:192634
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neo cassette replaced most of exon 3. Western blot analysis confirmed the absence of protein expression in the testes. (J:192634)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	14 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hormad2 Mutation:	32 strains or lines available

Original:	J:192634 Kogo H, et al., HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Genes Cells. 2012 Nov;17(11):897-912
All:	2 reference(s)