Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Them5tm1Hem
Name:	thioesterase superfamily member 5; targeted mutation 1, Brian A Hemmings
MGI ID:	MGI:5433219
Gene:	Them5  Location: Chr3:94249406-94254659 bp, + strand  Genetic Position: Chr3, 40.52 cM, cytoband F2
Alliance:	Them5tm1Hem page

Germline Transmission:	Earliest citation of germline transmission: J:186657
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     The translated portion of exon 1 and all of exon 2 were replace with an IRES-LacZ-neomycin cassette. (J:186657)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Them5 Mutation:	12 strains or lines available

Original:	J:186657 Zhuravleva E, et al., Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development. Mol Cell Biol. 2012 Jul;32(14):2685-97
All:	1 reference(s)