Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ddit4tm1.1Sinc
Name:	DNA-damage-inducible transcript 4; targeted mutation 1.1, Andrew Sinclair
MGI ID:	MGI:5432482
Gene:	Ddit4  Location: Chr10:59785497-59787592 bp, - strand  Genetic Position: Chr10, 29.66 cM, cytoband B3
Alliance:	Ddit4tm1.1Sinc page

Germline Transmission:	Earliest citation of germline transmission: J:186462
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 2. A neo cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed the coding sequence and the neo cassette. (J:186462)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

7 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddit4 Mutation:	17 strains or lines available

Original:	J:186462 Notini AJ, et al., Redd1 is a novel marker of testis development but is not required for normal male reproduction. Sex Dev. 2012;6(5):223-30
All:	1 reference(s)