Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trim72tm1Ygko
Name:	tripartite motif-containing 72; targeted mutation 1, Young-Gyu Ko
MGI ID:	MGI:5432128
Synonyms:	MG53-
Gene:	Trim72  Location: Chr7:127603121-127610205 bp, + strand  Genetic Position: Chr7, 69.89 cM
Alliance:	Trim72tm1Ygko page

Germline Transmission:	Earliest citation of germline transmission: J:186368
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons 1 through 3 were replaced with a neo cassette. Western blot analysis confirmed the absence of protein expression in skeletal muscle. (J:186368)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trim72 Mutation:	32 strains or lines available

Original:	J:186368 Lee CS, et al., TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1. Cell Death Differ. 2010 Aug;17(8):1254-65
All:	3 reference(s)